Portfolio
Research projects
Hereinafter a list of research Projects Citrech has participated:
- Ort-POR Sicilia - Innovation 14.10.05 Company Ortogel spa - POR Sicilia 2000/2006 – mis. 3.14 - Project n. 0198 entitled: “A new product “Citrus Soluble Fiber“ through optimisation of existing products by novel enzyme techniques.
- ”POR Sicilia – Innovation 16.10.2005 Company Cinzia alimentari srl - POR Sicilia 2000/2006 – mis. 3.14 – Project n. 0291 entitled: “Pectinesterase inactivation in citrus juices with cold-pasteurisation with high-pressure supercritical CO2”.
- POR Sicilia 2000-2006 mis. 3.14 – Company Agrumaria Corleone SpA Project entitled: “Membrane- Supramolecular Chemistry integrated technology for selective removal of pesticides from citrus essential oils“.
- Program PIA Innovation Project n. D08/0501/P 42300-13 – PIA REACOS Company Gioia Succhi Srl Decreto M.S.E. 1522320 del 1.12.2006 entitled “Novel methods for improve value of citrus by-products"; Projects “SAGRO“ POR Sicilia 2010 -2013 CUP G 63F11000470004
- Project“ SAGRO “ POR Sicilia 2010 -2013 CUP G 63F11000470004 Company Ortogel SpA “Third generations solar cells sensitized with natural autoctone pigments“.
- Project MISE Decr. 21 May 2014, G.U. Serie Generale n.134 del 12-06-2014 Company Citrofood SpA “Sustainable use of industrial citrus wastes“.
- Project PO FESR Sicilia 2014-2020 "New products from industrial processing of Mediterranean fruits and sustainable by-products management - MedFruit"
Dicono di Noi
Di seguito alcuni link relativi alla nostra attività:
http://www.felicitapubblica.it/tag/citrech/
http://www.agronomict.it/download/seminario%20pastazzo%20maggio%2016.pdf
http://www.cnr.it/dipartimenti/ProdottoDellaRicerca.html?cds=097&id=163462
http://www.cseicatania.com/public/file/2017-04-11-Materiale/Timpone.pdf
http://www.freshplaza.it/article/82788/Farina-di-pastazzo-una-risorsa-al-posto-dellolio-di-palma
http://www.lasiciliaweb.it/articolo/140195/sicilia/-il-pastazzo-al-posto-dellolio-di-palma
http://orangefiber.it/pastazzo-dagrumi-da-problema-a-risorsa/
http://cat.inist.fr/?aModele=afficheN&cpsidt=18491989
We Connect Buyers and Sellers
The connection between buyers and sellers is of fundamental importance to the proper functioning of any business. Whenever an interaction takes place between these two parties, a relationship is created based on the buying and selling of goods or services. This connection is important because it allows consumers to get what they need and sellers to gain income and support for their business.
Without an effective connection between buyers and sellers, the market would be chaotic and would not function properly. Buyers would not be able to find the products or services they need, while sellers would not have enough customers to sustain their business. The connection between these two parties creates a balance between supply and demand, allowing buyers to satisfy their needs and sellers to earn money.
Furthermore, the connection between buyers and sellers is important for the creation of trust between the two parties. When buyers are satisfied with their purchase, they are more likely to become loyal customers and recommend the product or service to others. Similarly, sellers who maintain a good reputation and offer quality products and services are more likely to attract new customers and retain existing ones.
With the advent of technology and online trading, the connection between buyers and sellers has become even more important. Through the use of the Internet, buyers can easily search for and compare products and services, while sellers can reach a larger and more diverse audience. In this way, the connection between buyers and sellers becomes crucial for the success of business activities and for the innovation of the products and services offered; the risk, however, is an excess of proposals that are not easily evaluated by the buyer. Collaboration with Citrech makes it possible to guide the choice of supplier in the best possible way.
In conclusion, the connection between buyers and sellers is a fundamental element for the proper functioning of the market and for the success of business activities. Without an effective and stable connection, trade and the economy could not exist efficiently and sustainably. For this reason, it is important to invest in creating and maintaining a good connection between buyers and sellers in order to ensure a prosperous future for both, and Citrech can help You with this.
Link Esterni/External links
Di seguito i link ad alcuni lavori scientifici sugli agrumi e a siti web esterni
Letteratura sugli Antociani - Anthocyanins Literature
Nelle tabelle seguenti riportiamo dei dati di letteratura sugli antociani relativi alla struttura, alle caratteristiche ed alle loro proprietà
Tabella 1 - Caratteristiche
| Authors | Year | Title | Journal | DOI |
|---|---|---|---|---|
| Alappat, B., Alappat, J. | 2020 | Anthocyanin Pigments: Beyond Aesthetics. | Molecules 25, 5500. | 001 |
| Taylor, L.P., Grotewold, E. | 2005 | Flavonoids as developmental regulators. | Current Opinion in Plant Biology 8, 317–323. | 002 |
| Goodwin T.W. | 1975 | The Flavonoids: Edited by J. B. Harbone, T. J. Mabry and Helga Mabry Chapman and Hall | FEBS Letters 60, 221–221. | 003 |
| Tanaka, Y., Sasaki, N., Ohmiya, A. | 2008 | Biosynthesis of plant pigments: anthocyanins, betalains and carotenoids. | The Plant Journal 54, 733–749. | 004 |
| Grotewold, E. | 2006 | The Genetics and Biochemistry of Floral Pigments. | Annu. Rev. Plant Biol. 57, 761–780. | 005 |
| He, F., Mu, L., Yan, G.L., Liang, N.N., Pan, Q.-H., Wang, J., Reeves, M.J., Duan, C.Q. | 2010 | Biosynthesis of Anthocyanins and Their Regulation in Colored Grapes. | Biosynthesis of Anthocyanins and Their Regulation in Colored Grapes. | 006 |
| Zhang, Y., Butelli, E., Martin, C. | 2014 | Engineering anthocyanin biosynthesis in plants. | Current Opinion in Plant Biology 19, 81–90. | 007 |
| Springob, K., Nakajima, J., Yamazaki, M., Saito, K. | 2003 | Springob, K., Nakajima, J., Yamazaki, M., Saito, K. | ChemInform 34, chin.200338265. | 008 |
| Kähkönen, M.P., Heinämäki, J., Ollilainen, V., Heinonen, M. | 2003 | Berry anthocyanins: isolation, identification and antioxidant activities. | Berry anthocyanins: isolation, identification and antioxidant activities. | 009 |
| Alfenito, M.R., Souer, E., Goodman, C.D., Buell, R., Mol, J., Koes, R., Walbot, V. | 1998 | Functional Complementation of Anthocyanin Sequestration in the Vacuole by Widely Divergent Glutathione S-Transferases. | The Plant Cell 10, 1135. | 010 |
| Marinova, K., Pourcel, L., Weder, B., Schwarz, M., Barron, D., Routaboul, J.-M., Debeaujon, I., Klein, M. | 2007 | The Arabidopsis MATE Transporter TT12 Acts as a Vacuolar Flavonoid/H+-Antiporter Active in Proanthocyanidin-Accumulating Cells of the Seed Coat. | The Plant Cell 19, 2023–2038. | 011 |
| Zhao, C.L., Chen, Z.J., Bai, X.S., Ding, C., Long, T.J., Wei, F.G., Miao, K.R., | 2014 | Zhao, C.L., Chen, Z.J., Bai, X.S., Ding, C., Long, T.J., Wei, F.G., Miao, K.R., | Zhao, C.L., Chen, Z.J., Bai, X.S., Ding, C., Long, T.J., Wei, F.G., Miao, K.R., | 012 |
Tabella 2 - Farmacocinetica
| Authors | Year | Title | Journal | DOI |
|---|---|---|---|---|
| He, J., Wallace, T.C., Keatley, K.E., Failla, M.L., Giusti, M.M. | 2009 | Stability of Black Raspberry Anthocyanins in the Digestive Tract Lumen and Transport Efficiency into Gastric and Small Intestinal Tissues in the Rat. | J. Agric. Food Chem. 57, 3141–3148. | 013 |
| Passamonti, S., Vrhovsek, U., Vanzo, A., Mattivi, F. | 2003 | The stomach as a site for anthocyanins absorption from food. | FEBS Letters 544, 210–213. | 014 |
| Talavéra, S., Felgines, C., Texier, O., Lamaison, J.-L., Besson, C., Rémésy, C. | 2003 | Anthocyanins Are Efficiently Absorbed from the Stomach in Anesthetized Rats. | The Journal of Nutrition 133, 4178–4182. | 015 |
| Felgines, C., Talavera, S., Texier, O., Gil-Izquierdo, A., Lamaison, J.-L., Remesy, C. | 205 | Felgines, C., Talavera, S., Texier, O., Gil-Izquierdo, A., Lamaison, J.-L., Remesy, C. | J. Agric. Food Chem. 53, 7721–7727. | 016 |
| Mazza, G., Kay, C.D., Cottrell, T., Holub, B.J. | 2002 | Absorption of Anthocyanins from Blueberries and Serum Antioxidant Status in Human Subjects. | J. Agric. Food Chem. 50, 7731–7737. | 018 |
| Prior, R.L., Wu, X., Cao, G. | 2002 | Absorption and Metabolism of Anthocyanins in Elderly Women after Consumption of Elderberry or Blueberry. | The Journal of Nutrition 132, 1865–1871. | 019 |
| Felgines, C., Talavéra, S., Texier, O., Lamaison, J.-L., Gonthier, M.-P., Scalbert, A., Rémésy, C. | 2003 | Strawberry Anthocyanins Are Recovered in Urine as Glucuro- and Sulfoconjugates in Humans. | The Journal of Nutrition 133, 1296–1301. | 020 |
| Kay, C.D., Mazza, G. (Joe), Holub, B.J. | 2005 | Anthocyanins Exist in the Circulation Primarily as Metabolites in Adult Men. | The Journal of Nutrition 135, 2582–2588. | 021 |
| Cooney, J.M., Jensen, D.J., McGhie, T.K. | 2004 | LC‐MS identification of anthocyanins in boysenberry extract and anthocyanin metabolites in human urine following dosing. | J Sci Food Agric 84, 237–245. | 022 |
| Wu, X., Pittman, H.E., Prior, R.L. | 2004 | Pelargonidin Is Absorbed and Metabolized Differently than Cyanidin after Marionberry Consumption in Pigs. | Pelargonidin Is Absorbed and Metabolized Differently than Cyanidin after Marionberry Consumption in Pigs. | 023 |
| Ichiyanagi, T., Shida, Y., Rahman, M.M., Hatano, Y., Konishi, T. | 2005 | Extended Glucuronidation Is Another Major Path of Cyanidin 3- O -β- d -Glucopyranoside Metabolism in Rats. | J. Agric. Food Chem. 53, 7312–7319. | 024 |
| Ichiyanagi, T., Shida, Y., Rahman, M.M., Hatano, Y., Konishi, T. | 2006 | Bioavailability and Tissue Distribution of Anthocyanins in Bilberry ( Vaccinium myrtillus L.) Extract in Rats. | J. Agric. Food Chem. 54, 6578–6587. | 025 |
| Walton, M.C., McGhie, T.K., Reynolds, G.W., Hendriks, W.H. | 2006 | The Flavonol Quercetin-3-Glucoside Inhibits Cyanidin-3-Glucoside Absorption in Vitro. | J. Agric. Food Chem. 54, 4913–4920. | 026 |
| Prior, R.L., Wu, X. | 2006 | Anthocyanins: Structural characteristics that result in unique metabolic patterns and biological activities. | Free Radical Research 40, 1014–1028. | 027 |
| Passamonti, S., Vrhovsek, U., Mattivi, F. | 2002 | The interaction of anthocyanins with bilitranslocase. | Biochemical and Biophysical Research Communications 296, 631–636. | 028 |
| Nicolin, V., Grill, V., Micali, F., Narducci, P., Passamonti, S. | 2005 | Immunolocalisation of bilitranslocase in mucosecretory and parietal cells of the rat gastric mucosa. | J Mol Hist 36, 45–50. | 029 |
| Talavéra, S., Felgines, C., Texier, O., Besson, C., Manach, C., Lamaison, J.-L., Rémésy, C. | 2004 | Anthocyanins Are Efficiently Absorbed from the Small Intestine in Rats. | The Journal of Nutrition 134, 2275–2279. | 030 |
| Matuschek, M.C., Hendriks, W.H., McGhie, T.K., Reynolds, G.W. | 2006 | The jejunum is the main site of absorption for anthocyanins in mice. | The Journal of Nutritional Biochemistry 17, 31–36. | 031 |
| Hollman, P.C.H. | 2004 | Absorption, Bioavailability, and Metabolism of Flavonoids. | Pharmaceutical Biology 42, 74–83. | 032 |
| Arts, I.C.W., Sesink, A.L.A., Faassen-Peters, M., Hollman, P.C.H., | 2004 | The type of sugar moiety is a major determinant of the small intestinal uptake and subsequent biliary excretion of dietary quercetin glycosides. | Br J Nutr 91, 841–847. | 033 |
| Manach, C., Williamson, G., Morand, C., Scalbert, A., Rémésy, C. | 2005 | Bioavailability and bioefficacy of polyphenols in humans. I. Review of 97 bioavailability studies. | he American Journal of Clinical Nutrition 81, 230S-242S. | 034 |
| Kay, C.D. | 2006 | Aspects of anthocyanin absorption, metabolism and pharmacokinetics in humans. | Nutr. Res. Rev. 19, 137–146. | 035 |
| Passamonti, S., Terdoslavich, M., Franca, R., Vanzo, A., Tramer, F., Braidot, E., Petrussa, E., Vianello, A. | 2009 | Bioavailability of Flavonoids: A Review of Their Membrane Transport and the Function of Bilitranslocase in Animal and Plant Organisms. | CDM 10, 369–394. | 036 |
| Kurilich, A.C., Clevidence, B.A., Britz, S.J., Simon, P.W., Novotny, J.A., | 2005 | Plasma and Urine Responses Are Lower for Acylated vs Nonacylated Anthocyanins from Raw and Cooked Purple Carrots. | J. Agric. Food Chem. 53, 6537–6542. | 037 |
| Mülleder, U., Murkovic, M., Pfannhauser, W. | 2002 | Urinary excretion of cyanidin glycosides. | Journal of Biochemical and Biophysical Methods 53, 61–66. | 038 |
| Kalt, W., Blumberg, J.B., McDonald, J.E., Vinqvist-Tymchuk, M.R., Fillmore, S.A.E., Graf, B.A., O’Leary, J.M., Milbury, P.E. | 2008 | Identification of Anthocyanins in the Liver, Eye, and Brain of Blueberry-Fed Pigs. | J. Agric. Food Chem. 56, 705–712. | 039 |
| Kay, C.D., Mazza, G., Holub, B.J., Wang, J., | 2004 | Anthocyanin metabolites in human urine and serum. | Br J Nutr 91, 933–942. | 040 |
| Milbury, P.E., Vita, J.A., Blumberg, J.B. | 2010 | Anthocyanins are Bioavailable in Humans following an Acute Dose of Cranberry Juice. | The Journal of Nutrition 140, 1099–1104. | 041 |
| Tsuda, T., Horio, F., Uchida, K., Aoki, H., Osawa, T. | 2003 | Dietary Cyanidin 3-O-β-D-Glucoside-Rich Purple Corn Color Prevents Obesity and Ameliorates Hyperglycemia in Mice. | The Journal of Nutrition 133, 2125–2130. | 042 |
| Williamson, G., Sies, H., Heber, D., Keen, C.L., Macdonald, I.A., Actis-Gorreta, L., Momma, T.Y., Ottaviani, J.I., Holt, R.R., Schroeter, H., Heiss, C. | 2009 | Functional foods for health promotion: state-of-the-science on dietary flavonoids | Extended abstracts from the 12 th Annual Conference on Functional Foods for Health Promotion. Nutrition Reviews 67, 736–743. | 043 |
| Keppler, K., Humpf, H.-U. | 2005 | Metabolism of anthocyanins and their phenolic degradation products by the intestinal microflora. | Bioorganic & Medicinal Chemistry 13, 5195–5205. | 044 |
| Sesso, H.D., Gaziano, J.M., Jenkins, D.J.A., Buring, J.E. | 2007 | Strawberry Intake, Lipids, C-Reactive Protein, and the Risk of Cardiovascular Disease in Women. | Journal of the American College of Nutrition 26, 303–310. | 045 |
| Klatsky, A. | 2001 | Commentary: Could abstinence from alcohol be hazardous to your health? | International Journal of Epidemiology 30, 739–742. | 046 |
| Aura, A.-M., Martin-Lopez, P., O’Leary, K.A., Williamson, G., Oksman-Caldentey, K.-M., Poutanen, K., Santos-Buelga, C. | 2005 | In vitro metabolism of anthocyanins by human gut microflora. | Eur J Nutr 44, 133–142. | 047 |
| Vitaglione, P., Donnarumma, G., Napolitano, A., Galvano, F., Gallo, A., Scalfi, L., Fogliano, V. | 2007 | Protocatechuic Acid Is the Major Human Metabolite of Cyanidin-Glucosides3. | The Journal of Nutrition 137, 2043–2048. | 048 |
| Crozier, A., Jaganath, I.B., Clifford, M.N. | 2009 | Dietary Phenolics: Chemistry, Bioavailability and Effects on Health. | ChemInform 40, chin.200946244. | 049 |
| Wallace, T.C. | 2011 | Anthocyanins in Cardiovascular Disease. | Advances in Nutrition 2, 1–7. | 050 |
| Nollet, L.M.L., Toldra, F. | 2012 | Anthocyanins and Betalains, in: Food Analysis by HPLC. | CRC Press, pp. 774–793. | 051 |
| Gonçalves, A.C., Nunes, A.R., Falcão, A., Alves, G., Silva, L.R. | 2021 | Dietary Effects of Anthocyanins in Human Health: A Comprehensive Review. | Pharmaceuticals 14, 690. | 052 |
Tabella 3 - Proprietà Antimicrobiche
| Authors | Year | Title | Journal | DOI |
|---|---|---|---|---|
| Nohynek, L.J., Alakomi, H.-L., Kähkönen, M.P., Heinonen, M., Helander, I.M., Oksman-Caldentey, K.-M., Puupponen-Pimiä, R.H. | 2006 | Antimicrobial Properties and Mechanisms of Action Against Severe Human Pathogens. | Berry Phenolics: Nutrition and Cancer 54, 18–32. | 053 |
| Burdulis, D., Ivanauskas, L., Dirsė, V., Kazlauskas, S., Ražukas, A., | 2007 | Study of diversity of anthocyanin composition in bilberry (Vaccinium myrtillus L.) fruits. | Medicina 43, 971. | 054 |
| Wu, V.C.-H., Qiu, X., Bushway, A., Harper, L. | 2008 | Antibacterial effects of American cranberry (Vaccinium macrocarpon) concentrate on foodborne pathogens. | LWT - Food Science and Technology 41, 1834–1841. | 055 |
| Česonienė, L., Jasutienė, I., Šarkinas, A. | 2009 | Phenolics and anthocyanins in berries of European cranberry and their antimicrobial activity. | Medicina 45, 992. | 056 |
| Lacombe, A., Wu, V.C.H., Tyler, S., Edwards, K. | 2010 | Antimicrobial action of the American cranberry constituents; phenolics, anthocyanins, and organic acids, against Escherichia coli O157:H7. | International Journal of Food Microbiology 139, 102–107. | 057 |
| Werlein, H.-D., Kütemeyer, C., Schatton, G., Hubbermann, E.M., Schwarz, K. | 2005 | Influence of elderberry and blackcurrant concentrates on the growth of microorganisms. | Food Control 16, 729–733. | 058 |
| Cisowska, A., Wojnicz, D., Hendrich, A.B. | 2011 | Anthocyanins as Antimicrobial Agents of Natural Plant Origin. | Natural Product Communications 6, 1934578X1100600. | 059 |
| Naz, S., Siddiqi, R., Ahmad, S., Rasool, S.A., Sayeed, S.A. | 2007 | Antibacterial Activity Directed Isolation of Compounds from Punica granatum. | Journal of Food Science 72. | 060 |
| Chatterjee, A., Yasmin, T., Bagchi, D., Stohs, S.J. | 2004 | Inhibition of Helicobacter pylori in vitro by various berry extracts, with enhanced susceptibility to clarithromycin. | Mol Cell Biochem 265, 19–26. | 061 |
| Smeriglio, A., Barreca, D., Bellocco, E., Trombetta, D. | 2016 | Chemistry, Pharmacology and Health Benefits of Anthocyanins. | Phytotherapy Research 30, 1265–1286. | 062 |
Tabella 4 - proprietà Anticancro
| Authors | Year | Title | Journal | DOI |
|---|---|---|---|---|
| Wang, C., Yu, S., Jiang, J., Li, H., Pan, Y., Li, W., Bai, C., Li, M., Xie, P., Liu, J., Li, J. | 2022 | Protective Effect of Anthocyanins on Radiation-induced Hippocampal Injurythrough Activation of SIRT3. | CPD 28, 1103–1108. | 063 |
| Durbin, R.P. | 1975 | Letter: Acid secretion by gastric mucous membrane. | Am J Physiol 229, 1726. | 064 |
| Xu, C., Li, C.Y.T., Kong, A.N.T.,ì | 2005 | Induction of phase I, II and III drug metabolism/transport by xenobiotics. | Arch Pharm Res 28, 249–268. | 065 |
| Xu, J.-W., Ikeda, K., Yamori, Y. | 2004 | Upregulation of Endothelial Nitric Oxide Synthase by Cyanidin-3-Glucoside, a Typical Anthocyanin Pigment. | Hypertension 44, 217–222. | 066 |
| Xu, J.-W., Ikeda, K., Yamori, Y. | 2004 | Cyanidin‐3‐glucoside regulates phosphorylation of endothelial nitric oxide synthase. | Cyanidin‐3‐glucoside regulates phosphorylation of endothelial nitric oxide synthase. | 068 |
| He, J., Giusti, M.M. | 2010 | Anthocyanins: Natural Colorants with Health-Promoting Properties. | Annu. Rev. Food Sci. Technol. 1, 163–187. | 069 |
| Renis, M., Calandra, L., Scifo, C., Tomasello, B., Cardile, V., Vanella, L., Bei, R., Fauci, L.L., Galvano, F. | 2008 | Response of cell cycle/stress-related protein expression and DNA damage upon treatment of CaCo2 cells with anthocyanins. | Br J Nutr 100, 27–35. | 070 |
| Bagchi, D., Sen, C.K., Bagchi, M., Atalay, M. | 2004 | Anti-angiogenic, Antioxidant, and Anti-carcinogenic Properties of a Novel Anthocyanin-Rich Berry Extract Formula. | Biochemistry (Moscow) 69, 75–80. | 071 |
| Singletary, K.W., Jung, K.-J., Giusti, M. | 2007 | Anthocyanin-Rich Grape Extract Blocks Breast Cell DNA Damage. | Journal of Medicinal Food 10, 244–251. | 072 |
| Srivastava, A., Akoh, C.C., Fischer, J., Krewer, G. | 2007 | Effect of Anthocyanin Fractions from Selected Cultivars of Georgia-Grown Blueberries on Apoptosis and Phase II Enzymes. | J. Agric. Food Chem. 55, 3180–3185. | 073 |
| Ohara, A., Matsuhisa, T., | 2004 | Effects of diet composition on mutagenic activity in urine. | BioFactors 22, 115–118. | 074 |
| Yoshimoto, M., Okuno, S., Yamaguchi, M., Yamakawa, O. | 2001 | Antimutagenicity of Deacylated Anthocyanins in Purple-fleshed Sweetpotato. | Bioscience, Biotechnology, and Biochemistry 65, 1652–1655. | 075 |
| Shih, P.-H., Yeh, C.-T., Yen, G.-C. | 2007 | Anthocyanins Induce the Activation of Phase II Enzymes through the Antioxidant Response Element Pathway against Oxidative Stress-Induced Apoptosis. | J. Agric. Food Chem. 55, 9427–9435. | 076 |
| Zhao, C., Giusti, M.M., Malik, M., Moyer, M.P., Magnuson, B.A. | 2004 | Effects of Commercial Anthocyanin-Rich Extracts on Colonic Cancer and Nontumorigenic Colonic Cell Growth. | J. Agric. Food Chem. 52, 6122–6128. | 077 |
| Chang, Y., Huang, H., Hsu, J., Yang, S., Wang, C. | 2005 | Anthocyanins rich extract-induced apoptotic cell death in human promyelocytic leukemia cells. | Toxicology and Applied Pharmacology 205, 201–212. | 078 |
| Feng, R., Ni, H.-M., Wang, S.Y., Tourkova, I.L., Shurin, M.R., Harada, H., Yin, X.-M. | 2007 | Cyanidin-3-rutinoside, a Natural Polyphenol Antioxidant, Selectively Kills Leukemic Cells by Induction of Oxidative Stress. | Journal of Biological Chemistry 282, 13468–13476. | 079 |
| Brandstetter, H., Grams, F., Glitz, D., Lang, A., Huber, R., Bode, W., Krell, H.-W., Engh, R.A. | 2001 | The 1.8-Å crystal structure of a matrix metalloproteinase 8-barbiturate inhibitor complex reveals a previously unobserved mechanism for collagenase substrate recognition. | Journal of Biological Chemistry 276, 31474. | 080 |
| Huang, C., Li, J., Song, L., Zhang, D., Tong, Q., Ding, M., Bowman, L., Aziz, R., Stoner, G.D. | 2006 | Black Raspberry Extracts Inhibit Benzo( a )Pyrene Diol-Epoxide–Induced Activator Protein 1 Activation and VEGF Transcription by Targeting the Phosphotidylinositol 3-Kinase/Akt Pathway. | Cancer Research 66, 581–587. | 081 |
| Jing, P., Bomser, J.A., Schwartz, S.J., He, J., Magnuson, B.A., Giusti, M.M. | 2008 | Structure−Function Relationships of Anthocyanins from Various Anthocyanin-Rich Extracts on the Inhibition of Colon Cancer Cell Growth. | J. Agric. Food Chem. 56, 9391–9398. | 083 |
| Zhang, Y., Seeram, N.P., Lee, R., Feng, L., Heber, D. | 2008 | Isolation and Identification of Strawberry Phenolics with Antioxidant and Human Cancer Cell Antiproliferative Properties. | J. Agric. Food Chem. 56, 670–675. | 082 |
| Kallam, K., Appelhagen, I., Luo, J., Albert, N., Zhang, H., Deroles, S., Hill, L., Findlay, K., Andersen, Ø.M., Davies, K., Martin, C. | 2017 | Aromatic Decoration Determines the Formation of Anthocyanic Vacuolar Inclusions. | Current Biology 27, 945–957. | 084 |
| Cvorovic, J., Tramer, F., Granzotto, M., Candussio, L., Decorti, G., Passamonti, S. | 2010 | Oxidative stress-based cytotoxicity of delphinidin and cyanidin in colon cancer cells. | Archives of Biochemistry and Biophysics 501, 151–157. | 085 |
| Hou, D.X., Ose, T., Lin, S., Harazoro, K., Imamura, I., Kubo, M., Uto, T., Terahara, N., Yoshimoto, M., Fujii, M. | 2003 | Anthocyanidins induce apoptosis in human promyelocytic leukemia cells: Structure-activity relationship and mechanisms involved. | Int J Oncol., Volume 23 Issue 3 | 086 |
| Forester, S.C., Waterhouse, A.L. | 2008 | Identification of Cabernet Sauvignon Anthocyanin Gut Microflora Metabolites. | J. Agric. Food Chem. 56, 9299–9304. | 087 |
| Seeram, N. | 2001 | Cyclooxygenase inhibitory and antioxidant cyanidin glycosides in cherries and berries. | Phytomedicine 8, 362–369. | 088 |
| Bruce, W.R., Wolever, T.M.S., Giacca, A., | 2000 | Mechanisms Linking Diet and Colorectal Cancer: The Possible Role of Insulin Resistance. | Nutrition and Cancer 37, 19–26. | 089 |
| Lala, G., Malik, M., Zhao, C., He, J., Kwon, Y., Giusti, M.M., Magnuson, B.A. | 2006 | Anthocyanin-Rich Extracts Inhibit Multiple Biomarkers of Colon Cancer in Rats. | Nutrition and Cancer 54, 84–93. | 090 |
| Kang, S.-Y., Seeram, N.P., Nair, M.G., Bourquin, L.D., | 2003 | Tart cherry anthocyanins inhibit tumor development in ApcMin mice and reduce proliferation of human colon cancer cells. | Cancer Letters 194, 13–19. | 091 |
| Cooke, D., Steward, W.P., Gescher, A.J., Marczylo, T. | 2005 | Anthocyans from fruits and vegetables – Does bright colour signal cancer chemopreventive activity? | European Journal of Cancer 41, 1931–1940. | 092 |
| Wang, L.-S., Stoner, G.D. | 2008 | Anthocyanins and their role in cancer prevention. | Cancer Letters 269, 281–290. | 093 |
| Thomasset, S., Teller, N., Cai, H., Marko, D., Berry, D.P., Steward, W.P., Gescher, A.J. | 2009 | Do anthocyanins and anthocyanidins, cancer chemopreventive pigments in the diet, merit development as potential drugs? | Cancer Chemother Pharmacol 64, 201–211. | 094 |
| Galvano, F., La Fauci, L., Lazzarino, G., Fogliano, V., Ritieni, A., Ciappellano, S., Battistini, N.C., Tavazzi, B., Galvano, G. | 2004 | Cyanidins: metabolism and biological properties. | The Journal of Nutritional Biochemistry 15, 2–11. | 095 |
| Hazafa, A., Rehman, K.-U.-, Jahan, N., Jabeen, Z., | 2020 | The Role of Polyphenol (Flavonoids) Compounds in the Treatment of Cancer Cells. | Nutrition and Cancer 72, 386–397. | 096 |
| Li, W., Peng, C., Zhaojie, L., Wei, W. | 2022 | Chemopreventive and therapeutic properties of anthocyanins in breast cancer: A comprehensive review. | Nutrition Research 107, 48–64. | 097 |
| Lin, B., Gong, C., Song, H., Cui, Y. | 2017 | Effects of anthocyanins on the prevention and treatment of cancer. | British J Pharmacology 174, 1226–1243. | 098 |
| De Sousa Moraes, L.F., Sun, X., Peluzio, M.D.C.G., Zhu, M.-J. | 2019 | Anthocyanins/anthocyanidins and colorectal cancer: What is behind the scenes? | Critical Reviews in Food Science and Nutrition 59, 59–71. | 099 |
| De Arruda Nascimento, E., De Lima Coutinho, L., Da Silva, C.J., De Lima, V.L.A.G., Dos Santos Aguiar, J. | 2022 | In vitro anticancer properties of anthocyanins: A systematic review. | Biochimica et Biophysica Acta (BBA) - Reviews on Cancer 1877, 188748. | 100 |
| Sehitoglu, M.H., Farooqi, A.A., Qureshi, M.Z., Butt, G., Aras, A. | 2014 | Anthocyanins: Targeting of Signaling Networks in Cancer Cells. | Asian Pacific Journal of Cancer Prevention 15, 2379–2381. | 101 |
| Dharmawansa, K.V.S., Hoskin, D.W., Rupasinghe, H.P.V. | 2020 | Chemopreventive Effect of Dietary Anthocyanins against Gastrointestinal Cancers: A Review of Recent Advances and Perspectives. | IJMS 21, 6555. | 102 |
| Jiang, W., Zhou, X. | 2019 | Hydrolysis of radish anthocyanins to enhance the antioxidant and antiproliferative capacities. | Food Chemistry 294, 477–485. | 103 |
| Liu, H., Jiang, W., Xie, M. | 2010 | Flavonoids: Recent Advances as Anticancer Drugs. | PRA 5, 152–164. | 104 |
| Chen, J., Xu, B., Sun, J., Jiang, X., Bai, W. | 2022 | Anthocyanin supplement as a dietary strategy in cancer prevention and management: A comprehensive review. | Critical Reviews in Food Science and Nutrition 62, 7242–7254. | 105 |
Tabella 5 - Malattie Metaboliche
| Authors | Year | Title | Journal | DOI |
|---|---|---|---|---|
| Zheng, Y., Ley, S.H., Hu, F.B. | 2018 | Global aetiology and epidemiology of type 2 diabetes mellitus and its complications. | Nat Rev Endocrinol 14, 88–98. | 106 |
| Belwal, T., Nabavi, S., Nabavi, S., Habtemariam, S. | 2017 | Dietary Anthocyanins and Insulin Resistance: When Food Becomes a Medicine. | Nutrients 9, 1111. | 107 |
| Sarikaphuti, A., Nararatwanchai, T., Hashiguchi, T., Ito, T., Thaworanunta, S., Kikuchi, K., Oyama, Y., Maruyama, I., Tancharoen, S. | 2013 | Preventive effects of Morus alba L. anthocyanins on diabetes in Zucker diabetic fatty rats. | Experimental and Therapeutic Medicine 6, 689–695. | 108 |
| Suantawee, T., Elazab, S., Hsu, W., Yao, S., Cheng, H., Adisakwattana, S. | 2017 | Cyanidin Stimulates Insulin Secretion and Pancreatic β-Cell Gene Expression through Activation of l-type Voltage-Dependent Ca2+ Channels. | Nutrients 9, 814. | 109 |
| Hong, S.H., Heo, J.I., Kim, J.H., Kwon, S.-O., Yeo, K.M., Bakowska-Barczak, A.M., Kolodziejczyk, P., Ryu, O.H., Choi, M.K., Kang, Y.H., Lim, S.S., Suh, H.-W., Huh, S.-O., Lee, J.-Y. | 2013 | Antidiabetic and Beta Cell-Protection Activities of Purple Corn Anthocyanins. | Biomolecules and Therapeutics 21, 284–289. | 110 |
| Matsui, T., Ebuchi, S., Kobayashi, M., Fukui, K., Sugita, K., Terahara, N., Matsumoto, K. | 2002 | Anti-hyperglycemic Effect of Diacylated Anthocyanin Derived from Ipomoea batatas Cultivar Ayamurasaki Can Be Achieved through the α-Glucosidase Inhibitory Action. | J. Agric. Food Chem. 50, 7244–7248. | 111 |
| Tsuda, T. | 2008 | Regulation of Adipocyte Function by Anthocyanins; Possibility of Preventing the Metabolic Syndrome. | J. Agric. Food Chem. 56, 642–646. | 112 |
| Tsuda, T., Ueno, Y., Yoshikawa, T., Kojo, H., Osawa, T. | 2006 | Microarray profiling of gene expression in human adipocytes in response to anthocyanins. | Biochemical Pharmacology 71, 1184–1197. | 113 |
| Tsuda, T., Ueno, Y., Kojo, H., Yoshikawa, T., Osawa, T. | 2005 | Gene expression profile of isolated rat adipocytes treated with anthocyanins. | Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 1733, 137–147. | 114 |
| Sasaki, R., Nishimura, N., Hoshino, H., Isa, Y., Kadowaki, M., Ichi, T., Tanaka, A., Nishiumi, S., Fukuda, I., Ashida, H., Horio, F., Tsuda, T. | 2007 | Cyanidin 3-glucoside ameliorates hyperglycemia and insulin sensitivity due to downregulation of retinol binding protein 4 expression in diabetic mice. | Biochemical Pharmacology 74, 1619–1627. | 115 |
| Channuwong, P., Salae, K., Chongruchiroj, S., Cheng, H., Suantawee, T., Thilavech, T., Adisakwattana, S. | 2022 | Dietary anthocyanins inhibit insulin fibril formation and cytotoxicity in 3T3-L1 preadipocytes. | International Journal of Biological Macromolecules 223, 1578–1585. | 116 |
| Saithong, T., Thilavech, T., Adisakwattana, S. | 2018 | Cyanidin-3-rutinoside reduces insulin fibrillation and attenuates insulin fibrils-induced oxidative hemolysis of human erythrocytes. | International Journal of Biological Macromolecules 113, 259–268. | 117 |
| Rambaran, R.N., Serpell, L.C. | 2008 | Amyloid fibrils: Abnormal protein assembly. | Prion 2, 112–117. | 118 |
| Choudhary, S., Kishore, N., Hosur, R.V. | 2015 | Inhibition of insulin fibrillation by osmolytes: Mechanistic Insights. | Sci Rep 5, 17599. | 119 |
| Shinohara, M., Sato, N. | 2017 | Bidirectional interactions between diabetes and Alzheimer’s disease. | Neurochemistry International 108, 296–302. | 120 |
| Raleigh, D., Zhang, X., Hastoy, B., Clark, A. | 2017 | The β-cell assassin: IAPP cytotoxicity. | Journal of Molecular Endocrinology 59, R121–R140. | 121 |
| Brange, J., Andersen, L., Laursen, E.D., Meyn, G., Rasmussen, E. | 1997 | Toward Understanding Insulin Fibrillation. | Journal of Pharmaceutical Sciences 86, 517–525. | 122 |
| Hua, Q., Weiss, M.A. | 2004 | Mechanism of Insulin Fibrillation. | Journal of Biological Chemistry 279, 21449–21460. | 123 |
| Van Den Berghe, G., Wouters, P., Weekers, F., Verwaest, C., Bruyninckx, F., Schetz, M., Vlasselaers, D., Ferdinande, P., Lauwers, P., Bouillon, R. | 2001 | Intensive Insulin Therapy in Critically Ill Patients. | N Engl J Med 345, 1359–1367. | 124 |
| Raskin, P., Allen, E., Hollander, P., Lewin, A., Gabbay, R.A., Hu, P., Bode, B., Garber, A. | 2005 | Initiating Insulin Therapy in Type 2 Diabetes. | Diabetes Care 28, 260–265. | 125 |
| Foderà, V., Librizzi, F., Groenning, M., Van De Weert, M., Leone, M. | 2008 | Secondary Nucleation and Accessible Surface in Insulin Amyloid Fibril Formation. | J. Phys. Chem. B 112, 3853–3858. | 126 |
| Rajasekhar, K., Chakrabarti, M., Govindaraju, T. | 2015 | Function and toxicity of amyloid beta and recent therapeutic interventions targeting amyloid beta in Alzheimer’s disease. | Chem. Commun. 51, 13434–13450. | 127 |
| Yoshihara, H., Saito, J., Tanabe, A., Amada, T., Asakura, T., Kitagawa, K., Asada, S. | 2016 | Characterization of Novel Insulin Fibrils That Show Strong Cytotoxicity Under Physiological pH. | Journal of Pharmaceutical Sciences 105, 1419–1426. | 128 |
| Tsuda, T. | 2012 | Dietary anthocyanin‐rich plants: Biochemical basis and recent progress in health benefits studies. | Molecular Nutrition Food Res 56, 159–170. | 129 |
| Mojica, L., Berhow, M., De Mejia, E.G. | 2017 | Black Bean Coat Anthocyanin‐Rich Extracts and Pure Anthocyanins Modulated Molecular Markers of Diabetes. | The FASEB Journal 31. | 130 |
Tabella 6 proprietà Antiossidanti
| Authors | Year | Title | Journal | DOI |
|---|---|---|---|---|
| Proteggente, A.R., Pannala, A.S., Paganga, G., Buren, L.V., Wagner, E., Wiseman, S., Put, F.V.D., Dacombe, C., Rice-Evans, C.A. | 2002 | The Antioxidant Activity of Regularly Consumed Fruit and Vegetables Reflects their Phenolic and Vitamin C Composition. | Free Radical Research 36, 217–233. | 131 |
| Seeram, N.P., Nair, M.G. | 2002 | Inhibition of Lipid Peroxidation and Structure−Activity-Related Studies of the Dietary Constituents Anthocyanins, Anthocyanidins, and Catechins. | J. Agric. Food Chem. 50, 5308–5312. | 132 |
| Jing, P., Zhao, S., Ruan, S., Sui, Z., Chen, L., Jiang, L., Qian, B. | 2014 | Quantitative studies on structure–ORAC relationships of anthocyanins from eggplant and radish using 3D-QSAR. | Food Chemistry 145, 365–371. | 133 |
| Kongpichitchoke, T., Hsu, J.L., Huang, T.C., | 2015 | Number of Hydroxyl Groups on the B-Ring of Flavonoids Affects Their Antioxidant Activity and Interaction with Phorbol Ester Binding Site of PKCδ C1B Domain: In Vitro and in Silico Studies. | J. Agric. Food Chem. 63, 4580–4586. | 134 |
| Huang, D., Ou, B., Prior, R.L. | 2005 | The Chemistry behind Antioxidant Capacity Assays. | J. Agric. Food Chem. 53, 1841–1856. | 135 |
| Wang, H., Cao, G., Prior, R.L. | 1997 | Oxygen Radical Absorbing Capacity of Anthocyanins. | J. Agric. Food Chem. 45, 304–309. | 136 |
| Acquaviva, R., Russo, A., Galvano, F., Galvano, G., Barcellona, M.L., Li Volti, G., Vanella, A. | 2003 | Cyanidin and cyanidin 3- O -β-D-glucoside as DNA cleavage protectors and antioxidants. | Cell Biol Toxicol 19, 243–252. | 137 |
| Serraino, I., Dugo, L., Dugo, P., Mondello, L., Mazzon, E., Dugo, G., Caputi, A.P., Cuzzocrea, S. | 2003 | Protective effects of cyanidin-3-O-glucoside from blackberry extract against peroxynitrite-induced endothelial dysfunction and vascular failure. | Life Sciences 73, 1097–1114. | 138 |
| Tarozzi, A., Marchesi, A., Hrelia, S., Angeloni, C., Andrisano, V., Fiori, J., Cantelli-Forti, G., Hrelia, P. | 2005 | Protective effects of Cyanidin-3-O-β-glucopyranoside against UVA-Induced Oxidative Stress in Human Keratinocytes. | Photochem Photobiol 2004-06-14-RA-200. | 139 |
| Cimino, F., Ambra, R., Canali, R., Saija, A., Virgili, F. | 2006 | Effect of Cyanidin-3- O -glucoside on UVB-Induced Response in Human Keratinocytes. | J. Agric. Food Chem. 54, 4041–4047. | 140 |
| Guerra, M.C., Galvano, F., Bonsi, L., Speroni, E., Costa, S., Renzulli, C., Cervellati, R. | 2005 | Cyanidin-3- O -β-glucopyranoside, a natural free-radical scavenger against aflatoxin B1- and ochratoxin A-induced cell damage in a human hepatoma cell line (Hep G2) and a human colonic adenocarcinoma cell line (CaCo-2). | Br J Nutr 94, 211–220. | 141 |
| Russo, A., La Fauci, L., Acquaviva, R., Campisi, A., Raciti, G., Scifo, C., Renis, M., Galvano, G., Vanella, A., Galvano, F., | 2005 | Ochratoxin A-induced DNA damage in human fibroblast: protective effect of cyanidin 3-O-β-d-glucoside. | The Journal of Nutritional Biochemistry 16, 31–37. | 142 |
| Szymanowska, U., Baraniak, B. | 2019 | Antioxidant and Potentially Anti-Inflammatory Activity of Anthocyanin Fractions from Pomace Obtained from Enzymatically Treated Raspberries. | Antioxidants 8, 299. | 143 |
| Lee, Y.-M., Yoon, Y., Yoon, H., Park, H.-M., Song, S., Yeum, K.-J. | 2017 | Dietary Anthocyanins against Obesity and Inflammation. | Nutrients 9, 1089. | 144 |
| Li, S., Wu, B., Fu, W., Reddivari, L., | 2019 | The Anti-inflammatory Effects of Dietary Anthocyanins against Ulcerative Colitis. | IJMS 20, 2588. | 145 |
| Pereira, S.R., Pereira, R., Figueiredo, I., Freitas, V., Dinis, T.C.P., Almeida, L.M. | 2017 | Comparison of anti-inflammatory activities of an anthocyanin-rich fraction from Portuguese blueberries (Vaccinium corymbosum L.) and 5-aminosalicylic acid in a TNBS-induced colitis rat model. | PLoS ONE 12, e0174116. | 146 |
| Ngamsamer, C., Sirivarasai, J., Sutjarit, N. | 2022 | The Benefits of Anthocyanins against Obesity-Induced Inflammation. | Biomolecules 12, 852. | 147 |
| Jayarathne, S., Stull, A.J., Park, O., Kim, J.H., Thompson, L., Moustaid‐Moussa, N. | 2019 | Protective Effects of Anthocyanins in Obesity‐Associated Inflammation and Changes in Gut Microbiome. | Molecular Nutrition Food Res 63, 1900149. | 148 |
| Azzini, E., Giacometti, J., Russo, G.L. | 2017 | Antiobesity Effects of Anthocyanins in Preclinical and Clinical Studies. | Oxidative Medicine and Cellular Longevity 2017, 1–11. | 149 |
| Thompson, K., Pederick, W., Santhakumar, A.B. | 2016 | Anthocyanins in obesity-associated thrombogenesis: a review of the potential mechanism of action. | Food Funct. 7, 2169–2178. | 150 |
| Knaup, B., Oehme, A., Valotis, A., Schreier, P. | 2009 | Anthocyanins as lipoxygenase inhibitors. | Molecular Nutrition Food Res 53, 617–624. | 151 |
| Singh, C.K., Siddiqui, I.A., El‐Abd, S., Mukhtar, H., Ahmad, N. | 2016 | Combination chemoprevention with grape antioxidants. | Molecular Nutrition Food Res 60, 1406–1415. | 152 |
| Phan, M.A.T., Bucknall, M.P., Arcot, J. | 2019 | Interferences of anthocyanins with the uptake of lycopene in Caco-2 cells, and their interactive effects on anti-oxidation and anti-inflammation in vitro and ex vivo. | Food Chemistry 276, 402–409. | 153 |
| Valenza, A., Bonfanti, C., Pasini, M.E., Bellosta, P. | 2018 | Anthocyanins Function as Anti-Inflammatory Agents in a Drosophila Model for Adipose Tissue Macrophage Infiltration. | BioMed Research International 2018, 1–9. | 154 |
Tabella 7 Applicazioni Oculari
| Authors | Year | Title | Journal | DOI |
|---|---|---|---|---|
| Matsumoto, H., Nakamura, Y., Iida, H., Ito, K., Ohguro, H. | 2006 | Comparative assessment of distribution of blackcurrant anthocyanins in rabbit and rat ocular tissues. | Experimental Eye Research 83, 348–356. | 155 |
| Nakaishi, H., Matsumoto, H., Tominaga, S., Hirayama, M. | 2000 | Effects of black current anthocyanoside intake on dark adaptation and VDT work-induced transient refractive alteration in healthy humans. | Altern Med Rev 5, 553–562. | |
| Pojer, E., Mattivi, F., Johnson, D., Stockley, C.S. | 2013 | The Case for Anthocyanin Consumption to Promote Human Health: A Review. | Comp Rev Food Sci Food Safe 12, 483–508. | 157 |
| Ohguro, H., Ohguro, I., Katai, M., Tanaka, S. | 2012 | Two-Year Randomized, Placebo-Controlled Study of Black Currant Anthocyanins on Visual Field in Glaucoma. | Ophthalmologica 228, 26–35. | 158 |
| Iida, H., Nakamura, Y., Matsumoto, H., Takeuchi, Y., Harano, S., Ishihara, M., Katsumi, O. | 2010 | Effect of Black-Currant Extract on Negative Lens-Induced Ocular Growth in Chicks. | Ophthalmic Res 44, 242–250. | 159 |
| Nabavi, S.F., Habtemariam, S., Daglia, M., Shafighi, N., Barber, A.J., Nabavi, S.M. | 2014 | Anthocyanins as a Potential Therapy for Diabetic Retinopathy. | CMC 22, 51–58. | 160 |
| Jin, X., Wang, C., Wu, W., Liu, T., Ji, B., Zhou, F. | 2018 | Cyanidin-3-glucoside Alleviates 4-Hydroxyhexenal-Induced NLRP3 Inflammasome Activation via JNK-c-Jun/AP-1 Pathway in Human Retinal Pigment Epithelial Cells. | Journal of Immunology Research 2018, 1–8. | 161 |
| Zhang, J., Liang, X., Li, X., Guan, Z., Liao, Z., Luo, Yun, Luo, Yunxia, | 2016 | Ocular delivery of cyanidin-3-glycoside in liposomes and its prevention of selenite-induced oxidative stress. | Drug Development and Industrial Pharmacy 42, 546–553. | 162 |
| Song, X.-L., Li, M.-J., Liu, Q., Hu, Z.-X., Xu, Z.-Y., Li, J.-H., Zheng, W.-L., Huang, X.-M., Xiao, F., Cui, Y.-H., Pan, H.-W. | 2020 | Cyanidin-3- O -glucoside Protects Lens Epithelial Cells against High Glucose-Induced Apoptosis and Prevents Cataract Formation via Suppressing NF-κB Activation and Cox-2 Expression. | J. Agric. Food Chem. 68, 8286–8294. | 163 |
| Kalt, W., McDonald, J.E., Fillmore, S.A.E., Tremblay, F. | 2014 | Blueberry Effects on Dark Vision and Recovery after Photobleaching: Placebo-Controlled Crossover Studies. | J. Agric. Food Chem. 62, 11180–11189. | 164 |
| Majumdar, S., Srirangam, R. | 2010 | Potential of the bioflavonoids in the prevention/treatment of ocular disorders. | Journal of Pharmacy and Pharmacology 62, 951–965. | 165 |
| Giannaccare, G., Pellegrini, M., Senni, C., Bernabei, F., Scorcia, V., Cicero, A.F.G. | 2020 | Clinical Applications of Astaxanthin in the Treatment of Ocular Diseases: Emerging Insights. | Marine Drugs 18, 239. | 166 |
| Wang, Y., Huo, Y., Zhao, L., Lu, F., Wang, O., Yang, X., Ji, B., Zhou, F., | 2016 | Cyanidin‐3‐glucoside and its phenolic acid metabolites attenuate visible light‐induced retinal degeneration in vivo via activation of Nrf2/HO‐1 pathway and NF‐κB suppression. | Molecular Nutrition Food Res 60, 1564–1577. | 167 |
| Nomi, Y., Iwasaki-Kurashige, K., Matsumoto, H. | 2019 | Therapeutic Effects of Anthocyanins for Vision and Eye Health. | Molecules 24, 3311. | 168 |
| Kosehira, M., Machida, N., Kitaichi, N. | 2020 | A 12-Week-Long Intake of Bilberry Extract (Vaccinium myrtillus L.) Improved Objective Findings of Ciliary Muscle Contraction of the Eye: A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Comparison Trial. | Nutrients 12, 600. | 169 |
Tabella 8 - Malattie Cardiovascolari
| Authors | Year | Title | Journal | DOI |
|---|---|---|---|---|
| Aviram, M., Kaplan, M., Rosenblat, M., Fuhrman, B. | 2005 | Dietary Antioxidants and Paraoxonases Against LDL Oxidation and Atherosclerosis Development | Atherosclerosis: Diet and Drugs, Handbook of Experimental Pharmacology. Springer Berlin Heidelberg, Berlin, Heidelberg, pp. 263–300. | 170 |
| Serban, C., Sahebkar, A., Ursoniu, S., Andrica, F., Banach, M. | 2015 | Effect of sour tea (Hibiscus sabdariffa L.) on arterial hypertension: a systematic review and meta-analysis of randomized controlled trials. | Journal of Hypertension 33, 1119–1127. | 171 |
| Wallace, T., Slavin, M., Frankenfeld, C. | 2016 | Systematic Review of Anthocyanins and Markers of Cardiovascular Disease. | Nutrients 8, 32. | 172 |
| Wang, X., Ouyang, Y.Y., Liu, J., Zhao, G. | 2014 | Flavonoid intake and risk of CVD: a systematic review and meta-analysis of prospective cohort studies. | Br J Nutr 111, 1–11. | 173 |
| Hassellund, S.S., Flaa, A., Kjeldsen, S.E., Seljeflot, I., Karlsen, A., Erlund, I., Rostrup, M. | 2013 | Effects of anthocyanins on cardiovascular risk factors and inflammation in pre-hypertensive men: a double-blind randomized placebo-controlled crossover study. | J Hum Hypertens 27, 100–106. | 174 |
| Sorrenti, V., Mazza, F., Campisi, A., Di Giacomo, C., Acquaviva, R., Vanella, L., Galvano, F. | 2007 | Heme oxygenase induction by cyanidin‐3‐O‐β‐glucoside in cultured human endothelial cells. | Molecular Nutrition Food Res 51, 580–586. | 175 |
| Garcia-Alonso, M., Minihane, A.M., Rimbach, G., Rivas-Gonzalo, J.C., De Pascual-Teresa, S. | 2009 | Red wine anthocyanins are rapidly absorbed in humans and affect monocyte chemoattractant protein 1 levels and antioxidant capacity of plasma. | The Journal of Nutritional Biochemistry 20, 521–529. | 176 |
| Mauray, A., Felgines, C., Morand, C., Mazur, A., Scalbert, A., Milenkovic, D. | 2012 | Bilberry anthocyanin-rich extract alters expression of genes related to atherosclerosis development in aorta of apo E-deficient mice. | Nutrition, Metabolism and Cardiovascular Diseases 22, 72–80. | 177 |
| Tsuda, T., Shiga, K., Ohshima, K., Kawakishi, S., Osawa, T. | 1996 | Inhibition of lipid peroxidation and the active oxygen radical scavenging effect of anthocyanin pigments isolated from Phaseolus vulgaris L. | Biochemical Pharmacology 52, 1033–1039. | 178 |
| Dong, Y., Wu, X., Han, L., Bian, J., He, C., El-Omar, E., Gong, L., Wang, M. | 2022 | The Potential Roles of Dietary Anthocyanins in Inhibiting Vascular Endothelial Cell Senescence and Preventing Cardiovascular Diseases. | Nutrients 14, 2836. | 179 |
| Cassidy, A. | 2018 | Berry anthocyanin intake and cardiovascular health. | Molecular Aspects of Medicine 61, 76–82. | 180 |
| Danielewski, M., Matuszewska, A., Nowak, B., Kucharska, A.Z., Sozański, T. | 2020 | The Effects of Natural Iridoids and Anthocyanins on Selected Parameters of Liver and Cardiovascular System Functions. | Oxidative Medicine and Cellular Longevity, 1-12 | 181 |
| Reis, J.F., Monteiro, V.V.S., De Souza Gomes, R., Do Carmo, M.M., Da Costa, G.V., Ribera, P.C., Monteiro, M.C. | 2016 | Action mechanism and cardiovascular effect of anthocyanins: a systematic review of animal and human studies. | J Transl Med 14, 315. | 182 |
| De Pascual-Teresa, S. | 2014 | Molecular mechanisms involved in the cardiovascular and neuroprotective effects of anthocyanins. | Archives of Biochemistry and Biophysics 559, 68–74. | 183 |
| Varghese, R., George Priya Doss, C., Kumar, R.S., Almansour, A.I., Arumugam, N., Efferth, T., Ramamoorthy, S. | 2022 | Cardioprotective effects of phytopigments via multiple signaling pathways. | Phytomedicine 95, 153859. | 184 |
| Dellagli, M. | 2004 | Vascular effects of wine polyphenols. | Cardiovascular Research 63, 593–602. | 185 |
Tabella 9 - Benessere Cerebrale
| Authors | Year | Title | Journal | DOI |
|---|---|---|---|---|
| Rendeiro, C., Guerreiro, J.D.T., Williams, C.M., Spencer, J.P.E. | 2012 | Flavonoids as modulators of memory and learning: molecular interactions resulting in behavioural effects. | Proc. Nutr. Soc. 71, 246–262. | 186 |
| Shukitt-Hale, B., Kalt, W., Carey, A.N., Vinqvist-Tymchuk, M., McDonald, J., Joseph, J.A. | 2009 | Plum juice, but not dried plum powder, is effective in mitigating cognitive deficits in aged rats. | Nutrition 25, 567–573. | 187 |
| Spencer, J.P.E. | 2010 | The impact of fruit flavonoids on memory and cognition. | Br J Nutr 104, S40–S47. | 188 |
| Goyarzu, P., Malin, D.H., Lau, F.C., Taglialatela, G., Moon, W.D., Jennings, R., Moy, E., Moy, D., Lippold, S., Shukitt-Hale, B., Joseph, J.A. | 2004 | Blueberry Supplemented Diet: Effects on Object Recognition Memory and Nuclear Factor-kappa B Levels in Aged Rats. | Nutritional Neuroscience 7, 75–83. | 189189 |
| Shukitt-Hale, B., Lau, F.C., Carey, A.N., Galli, R.L., Spangler, E.L., Ingram, D.K., Joseph, J.A. | 2008 | Blueberry polyphenols attenuate kainic acid-induced decrements in cognition and alter inflammatory gene expression in rat hippocampus. | Nutritional Neuroscience 11, 172–182. | 190 |
| Galli, R., Bielinski, D., Szprengiel, A., Shukitthale, B., Joseph, J. | 2006 | Blueberry supplemented diet reverses age-related decline in hippocampal HSP70 neuroprotection. | Neurobiology of Aging 27, 344–350. | 191 |
| Ramirez, M., Izquierdo, I., Raseira, M., Zuanazzi, J., Barros, D., Henriques, A. | 2005 | Effect of lyophilised berries on memory, anxiety and locomotion in adult rats. | Pharmacological Research 52, 457–462. | 192 |
| Joseph, J.A., Arendash, G., Gordon, M., Diamond, D., Shukitt-Hale, B., Morgan, D., Denisova, N.A. | 2003 | Blueberry Supplementation Enhances Signaling and Prevents Behavioral Deficits in an Alzheimer Disease Model. | Nutritional Neuroscience 6, 153–162. | 193 |
| Krikorian, R., Nash, T.A., Shidler, M.D., Shukitt-Hale, B., Joseph, J.A. | 2010 | Concord grape juice supplementation improves memory function in older adults with mild cognitive impairment. | Br J Nutr 103, 730–734. | 194 |
| Banji, O.J.F., Banji, D., Makeen, H.A., Alqahtani, S.S., Alshahrani, S. | 2022 | Neuroinflammation: The Role of Anthocyanins as Neuroprotectants. | CN 20, 2156–2174. | 195 |
| Afzal, M., Redha, A., AlHasan, R., | 2019 | Anthocyanins Potentially Contribute to Defense against Alzheimer’s Disease. | Molecules 24, 4255. | 196 |
| Panchal, S.K., Brown, L. | 2022 | Potential Benefits of Anthocyanins in Chronic Disorders of the Central Nervous System. | Molecules 28, 80. | 197 |
| Zhong, H., Xu, J., Yang, M., Hussain, M., Liu, X., Feng, F., Guan, R. | 2023 | Protective effect of Anthocyanins against Neurodegenerative Diseases through the Microbial-Intestinal-Brain Axis: A Critical Review. | Protective Effect of Nutrients 15, 496. | 198 |
| Tran, P.H.L., Tran, T.T.D. | 2021 | Blueberry Supplementation in Neuronal Health and Protective Technologies for Efficient Delivery of Blueberry Anthocyanins. | Biomolecules 11, 102. | 199 |
Contact Informations
Address
Viale Regina Margherita, 61
98121 Messina
Italia
Tel: (+39) 090 5731424
Mob. 1 (+39) 335 440930
Mob. 2 (+39) 338 5004853
Fax: (+39) 090 5731424
Mon / Fri: 8:30am - 6:00pm
